BDBM319676 2-{1-[2-(4-ethylphenyl)ethyl]-1H-imidazol-4-yl}-4- [5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]pyridine::US10174003, Example 95::US9896436, Example 95

SMILES CCc1ccc(CCn2cnc(-c3cc(-c4nn[nH]c4C(F)(F)F)ccn3)c2)cc1

InChI Key InChIKey=YUQUVIKPEWMIPQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 319676   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319676BDBM319676(2-{1-[2-(4-ethylphenyl)ethyl]-1H-imidazol-4-yl}-4-...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319676BDBM319676(2-{1-[2-(4-ethylphenyl)ethyl]-1H-imidazol-4-yl}-4-...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319676BDBM319676(2-{1-[2-(4-ethylphenyl)ethyl]-1H-imidazol-4-yl}-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319676BDBM319676(2-{1-[2-(4-ethylphenyl)ethyl]-1H-imidazol-4-yl}-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent