BDBM319829 US10174015, Compound 42

SMILES Clc1cccc(Oc2ccc(cc2)C(=O)N2CCOC2=O)c1

InChI Key InChIKey=DQYFBMJULCWIFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319829   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Xiamen University

US Patent
LigandPNGBDBM319829(US10174015, Compound 42)
Affinity DataIC50: 370nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM319829(US10174015, Compound 42)
Affinity DataIC50: 7.74E+3nMAssay Description:Inhibition of rat NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Xiamen University

US Patent
LigandPNGBDBM319829(US10174015, Compound 42)
Affinity DataIC50: 1.00E+5nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent