BDBM319938 3-[(2- Methylpyridin- 4-yl)oxy]-5- (5-methyl- 1,3-thiazol-2- yl)-N-{(1R)-1- [6- (trifluorometh- yl)pyridazin- 3- yl]ethyl} benzamide::US10174016, Example 105::US10202369, Example 105::US10472354, Example 105

SMILES C[C@@H](NC(=O)c1cc(Oc2ccnc(C)c2)cc(c1)-c1ncc(C)s1)c1ccc(nn1)C(F)(F)F

InChI Key InChIKey=DZQXNDYGTRQHHO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 319938   

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 6nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 6nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 6nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 6nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetP2X purinoceptor 2(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent