BDBM320284 1,4-Dimethyl-5-[7-(1-methyl-1H-pyrazol-5-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl]-1H-1,2,3-triazole::US10174024, Example 1

SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)-c1ccnn1C

InChI Key InChIKey=WFJBZLUSRUIVJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320284   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320284(US10174024, Example 1 | 1,4-Dimethyl-5-[7-(1-methy...)
Affinity DataIC50: 5nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent