BDBM320291 2-{4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-8-yl]piperidin-1-yl}-2-oxoethyl acetate::US10174024, Example 8

SMILES CC(=O)OCC(=O)N1CCC(CC1)c1ccc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2c1)-c1c(C)nnn1C

InChI Key InChIKey=OOGSDKBASDHRBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320291   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320291(US10174024, Example 8 | 2-{4-[3-(Dimethyl-1H-1,2,3...)
Affinity DataIC50: 5nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent