BDBM320357 1-{5-[(4,4-Difluorocyclohexyl)(phenyl)methyl]-3-(dimethyl-1H-1,2,3-triazol-5-yl)-5H-pyrido[3,2-b]indol-7-yl}-4,4-difluoropiperidine::US10174024, Example 75::US10174024, Example 76

SMILES Cc1nnn(C)c1-c1cnc2c(c1)n(C(C1CCC(F)(F)CC1)c1ccccc1)c1cc(ccc21)N1CCC(F)(F)CC1

InChI Key InChIKey=IXLLZKOCQYEIAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320357   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320357(US10174024, Example 75 | US10174024, Example 76 | ...)
Affinity DataIC50: 5nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320357(US10174024, Example 75 | US10174024, Example 76 | ...)
Affinity DataIC50: 5nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent