BDBM320435 2-(1,2,3,4- tetrahydroquinolylcarbonyl)- pyrrolo[3,2-b]-pyridine-7- carboxylic acid::US10174026, Example 105::US9738637, Example 105

SMILES O=C(O)c1ccnc2cc(C(=O)N3CCCc4ccccc43)[nH]c12

InChI Key InChIKey=XPBKVYOBTSXQJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320435   

TargetLysine-specific demethylase 5A(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320435BDBM320435(US10174026, Example 105 | 2-(1,2,3,4- tetrahydroqu...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320435BDBM320435(US10174026, Example 105 | 2-(1,2,3,4- tetrahydroqu...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320435BDBM320435(US10174026, Example 105 | 2-(1,2,3,4- tetrahydroqu...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent