BDBM321070 (S)-8-((2-amino-4-methylpentyl)oxy)-4,5,9-trimethylbenzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 4

SMILES CC(C)C[C@H](N)COc1cc2c(cc1C)c1ccnc(C)c1n(C)c2=O

InChI Key InChIKey=CWBFWTAEEAPMOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321070   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321070((S)-8-((2-amino-4-methylpentyl)oxy)-4,5,9-trimethy...)
Affinity DataIC50: 14nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent