BDBM321083 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-2,5-dimethylbenzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 18

SMILES CC(C)C[C@](C)(N)COc1ccc2c3cc(C)ncc3n(C)c(=O)c2c1Cl

InChI Key InChIKey=APVDCBPZILLTJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321083   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321083((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-2...)
Affinity DataIC50: 3nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent