BDBM321085 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-2,5,7-trimethylbenzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 20

SMILES CC(C)C[C@](C)(N)COc1ccc2c3cc(C)ncc3n(C)c(=O)c2c1C

InChI Key InChIKey=FJJVBFKXDQPLRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321085   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321085((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-2,5,7-trim...)
Affinity DataIC50: 4.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent