BDBM321089 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-5-cyclopropyl-4-methyl-6-oxo-5,6-dihydrobenzo[c][1,7]naphthyridine-9-carbonitrile::US10174044, Example 24

SMILES CC(C)C[C@](C)(N)COc1cc2c(cc1C#N)c1ccnc(C)c1n(C1CC1)c2=O

InChI Key InChIKey=FBPULJJUCUFAHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321089   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321089((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-5-cyclopro...)
Affinity DataIC50: 69nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent