BDBM321129 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isochromeno[3,4-c]pyridin-4-amine::US10174044, Example 60

SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3c(N)nccc-23)c1

InChI Key InChIKey=AHTZQLQDCDGRHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321129   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321129((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-6H-isochro...)
Affinity DataIC50: 0.740nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent