BDBM321130 (S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6H-isochromeno[3,4-c]pyridin-2-amine::US10174044, Example 61

SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(N)cc-23)c1Cl

InChI Key InChIKey=JUXPRFDTJSOLCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321130   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321130(US10174044, Example 61 | (S)-8-((2-amino-2,4-dimet...)
Affinity DataIC50: 0.410nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent