BDBM321324 US10179791, Compound 182::US10807991, Compound 182

SMILES CCc1ccc(Cl)c(c1)C1CC1c1ccc2c(OCC22CCN(CCC(O)=O)CC2)c1

InChI Key InChIKey=PTSIGHMEPRYBLD-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 321324   

TargetSphingosine 1-phosphate receptor 5(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50:  39.8nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 5(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50:  39.8nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50: >3.16E+3nMAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog n°: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50: <3.16E+3nMAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50: >1.00E+4nMAssay Description:The CHO-human-S1P3-Aeqorin assay (CHO/Gal6/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (acces...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Abbvie

US Patent
LigandPNGBDBM321324(US10179791, Compound 182 | US10807991, Compound 18...)
Affinity DataEC50: <1.00E+4nMAssay Description:The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent