BDBM322800 6-(4-((2-(cyclohexyl(methyl)amino)-5- oxo-5,6-dihydropyrimido[4,5-d]pyridazin- 4-yl)amino)phenyl)-6-azaspiro[2.5]octane- 1-carboxylic acid::US10183944, Example 170::US10647720, Ex. # 170
SMILES CN(C1CCCCC1)c1nc(Nc2ccc(cc2)N2CCC3(CC3C(O)=O)CC2)c2c(cn[nH]c2=O)n1
InChI Key InChIKey=AEOFZJRNFSIFIE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322800
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair