BDBM322814 2-(azepan-1-yl)-4-((4-(2-(4-hydroxy-4- methylpiperidin-1-yl)ethoxy)phenyl) amino)pyrimido[4,5-d]pyridazin-5(6H)- one::US10183944, Example 184::US10647720, Ex. # 184
SMILES CC1(O)CCN(CCOc2ccc(Nc3nc(nc(C=N)c3C(N)=O)N3CCCCCC3)cc2)CC1
InChI Key InChIKey=YRFHNXRTSFKGBP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322814
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair