BDBM322823 2-(1-(5-oxo-4-((4-(piperazin-1-yl)phenyl) amino)-5,6-dihydropyrimido[4,5- d]pyridazin-2-yl)piperidin-4- yl)acetonitrile::US10183944, Example 193::US10647720, Ex. # 193
SMILES NC(=O)c1c(Nc2ccc(cc2)N2CCNCC2)nc(nc1C=N)N1CCC(CC#N)CC1
InChI Key InChIKey=AKJJKLBDNXRNNX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322823
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair