BDBM322985 1-[5-tert-butyl-7-(2-methylpyrazol-3-yl)triazolo[4,5-d]pyrimidin-3-yl]-4,4,4-trifluorobutan-2-ol::US10183946, Example 16

SMILES Cn1nccc1-c1nc(nc2n(CC(O)CC(F)(F)F)nnc12)C(C)(C)C

InChI Key InChIKey=WMHGKQGZCSXLEJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322985   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322985(US10183946, Example 16 | 1-[5-tert-butyl-7-(2-meth...)
Affinity DataEC50:  42.4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322985(US10183946, Example 16 | 1-[5-tert-butyl-7-(2-meth...)
Affinity DataEC50: >1.00E+4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent