BDBM322988 5-tert-butyl-7-(2-methylpyrazol-3-yl)-3-(oxetan-3-yl)triazolo[4,5-d]pyrimidine::US10183946, Example 19

SMILES Cn1nccc1-c1nc(nc2n(nnc12)C1COC1)C(C)(C)C

InChI Key InChIKey=PTYPLPZSYHEZNT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322988   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322988(US10183946, Example 19 | 5-tert-butyl-7-(2-methylp...)
Affinity DataEC50:  190nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322988(US10183946, Example 19 | 5-tert-butyl-7-(2-methylp...)
Affinity DataEC50: >1.00E+4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent