BDBM322997 5-tert-butyl-7-(1H-imidazol-2-yl)-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidine::US10183946, Example 28

SMILES Cn1nnnc1Cn1nnc2c(nc(nc12)C(C)(C)C)-c1ncc[nH]1

InChI Key InChIKey=IYCZANKUKRKAJD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322997   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322997(US10183946, Example 28 | 5-tert-butyl-7-(1H-imidaz...)
Affinity DataEC50:  12.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM322997(US10183946, Example 28 | 5-tert-butyl-7-(1H-imidaz...)
Affinity DataEC50: >1.00E+4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent