BDBM323008 3-[5-tert-Butyl-3-[(2-chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]thietan-3-ol::US10183946, Example 39

SMILES CC(C)(C)c1nc(c2nnn(Cc3ccccc3Cl)c2n1)C1(O)CSC1

InChI Key InChIKey=DNVYUDKJKAUFRX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323008   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM323008(US10183946, Example 39 | 3-[5-tert-Butyl-3-[(2-chl...)
Affinity DataEC50:  168nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM323008(US10183946, Example 39 | 3-[5-tert-Butyl-3-[(2-chl...)
Affinity DataEC50: >1.00E+4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent