BDBM323030 (1R,2R and 1S,2S)-N-(5-Methoxy-1- methyl-1H-pyrazol-4-yl)-2-[4-(1H-pyrazol- 3-yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 14::US10508119, Example 14

SMILES COc1c(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2cc[nH]n2)cnn1C

InChI Key InChIKey=NOGGAYCFBWOSDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323030   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323030(US10183947, Example 14 | (1R,2R and 1S,2S)-N-(5-Me...)
Affinity DataIC50: 400nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent