BDBM323049 4-[({(1R,2R and 1S,2S)-2-[2-Chloro-4-(3- methyl-1H-pyrazol-5-yl)benzoyl] cyclohexyl}carbonyl)amino]-1-methyl-1H- pyrazole-5-carboxamide::US10183947, Example 32::US10508119, Example 32

SMILES Cc1cc([nH]n1)-c1ccc(C(=O)C2CCCCC2C(=O)Nc2cnn(C)c2C(N)=O)c(Cl)c1

InChI Key InChIKey=OOYXLFCYTLLMDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323049   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323049(US10183947, Example 32 | 4-[({(1R,2R and 1S,2S)-2-...)
Affinity DataIC50: 170nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent