BDBM32309 6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-dione::6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-quinone::MLS000723157::SMR000236093::cid_2151868

SMILES COc1ccc(c(OC)c1)-n1c(=O)c2ccccc2c2ccccc2c1=O

InChI Key InChIKey=QQRNWVHTGXOENQ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32309   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32309(6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.28E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32309(6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.74E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32309(6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  2.69E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32309(6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.34E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32309(6-(2,4-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.63E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay