BDBM323149 US9630931, Example 12

SMILES Clc1cc(NC(=O)Nc2cnc(cn2)C#N)ccc1CCNCC1CCCCC1

InChI Key InChIKey=BSTRBQNADQFYMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323149   

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM323149(US9630931, Example 12)
Affinity DataIC50: 30nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent