BDBM323246 3,4-Dichloro-5-cyanobenzyl 4-(4-(1H-1,2,3-triazol-4-yl)butanamido)piperidine-1-carboxylate::US9630945, 72

SMILES Clc1cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)cc(C#N)c1Cl

InChI Key InChIKey=PGIXVLGVPDYHGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323246   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM323246(3,4-Dichloro-5-cyanobenzyl 4-(4-(1H-1,2,3-triazol-...)
Affinity DataIC50: 7nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent