BDBM323260 3-(1H-Imidazol-4-yl)-N-[(R)-1-(4-methoxybenzyl)-2-oxo-2-[3-o-tolyl-3-(4,4,4-trifluorobutoxy)azetidin-1-yl]ethyl]propionamide::US9630949, 78

SMILES COc1ccc(C[C@@H](NC(=O)CCc2c[nH]cn2)C(=O)N2CC(C2)(OCCCC(F)(F)F)c2ccccc2C)cc1

InChI Key InChIKey=XRANRYVURXULMT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323260   

TargetMelanocyte-stimulating hormone receptor(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM323260(3-(1H-Imidazol-4-yl)-N-[(R)-1-(4-methoxybenzyl)-2-...)
Affinity DataEC50:  120nMAssay Description:In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM323260(3-(1H-Imidazol-4-yl)-N-[(R)-1-(4-methoxybenzyl)-2-...)
Affinity DataEC50:  2.00E+3nMAssay Description:In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent