BDBM323703 (R)-3-(2-ethoxypyridin-3-yloxy)-N-ethyl-3-phenylpropan-1-amine::US10188758, Example 5

SMILES CCNCC[C@@H](Oc1cccnc1OCC)c1ccccc1

InChI Key InChIKey=FDUKXVZUSDZNAD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323703   

TargetSodium-dependent noradrenaline transporter(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM323703((R)-3-(2-ethoxypyridin-3-yloxy)-N-ethyl-3-phenylpr...)
Affinity DataKi:  37.3nMAssay Description:Assay Type: BindingSpecies: HumanOrigin: Recombinant/CHO cellsLigand: [3H]-NisoxetineLigand [M]: 1.00E-09Kd (Binding Affinity): 3.00E-09Bmax: 10 pmol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM323703((R)-3-(2-ethoxypyridin-3-yloxy)-N-ethyl-3-phenylpr...)
Affinity DataKi:  579nMAssay Description:Assay Type: BindingSpecies: HumanOrigin: PlateletsLigand: [3H]Citalopram, N-MethylLigand [M]: 7.00E-10Kd (Binding Affinity): 2.50E-09Bmax: 425 fmol/m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent