BDBM324146 US10189816, Compound 139

SMILES COc1ccc(cc1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1)C(C)C

InChI Key InChIKey=ABLAUHBDGOJXMC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324146   

TargetEnvelope glycoprotein gp160(HIV-1)
Viiv Healthcare UK (NO.5)

US Patent
LigandPNGBDBM324146(US10189816, Compound 139)
Affinity DataEC50:  30nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetEnvelope glycoprotein gp160(HIV-1)
Viiv Healthcare UK (NO.5)

US Patent
LigandPNGBDBM324146(US10189816, Compound 139)
Affinity DataEC50: <100nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent