BDBM324401 3-N-(4'-N-mPEG3-piperazinyl) 5-fluoro lamotrigine::US10189859, Compound 104

SMILES COCCOCCOCCOCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=YOJIEQMJUGHGQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324401   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM324401(3-N-(4'-N-mPEG3-piperazinyl) 5-fluoro lamotrigine ...)
Affinity DataIC50: <5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM324401(3-N-(4'-N-mPEG3-piperazinyl) 5-fluoro lamotrigine ...)
Affinity DataIC50: >2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent