BDBM324662 1''-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H-indol-2- yl}methyl)spiro[cyclopropane-1,3''- pyrrolo[2,3-c]pyridin]-2''(1''H)-one::US10189838, Example 3-3::US10189838, Example 9

SMILES CS(=O)(=O)CCn1c(CN2C(=O)C3(CC3)c3ccncc23)cc2cc(Cl)ccc12

InChI Key InChIKey=CPPVZYYUTPWQKU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324662   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent