BDBM324740 1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- benzimidazol-2-yl}methyl)-4'- fluorospiro[cyclopropane-1,3'-indol]- 2'(1'H)-one::US10189838, Example 34-2

SMILES CS(=O)(=O)CCn1c(CN2C(=O)C3(CC3)c3c2cccc3F)nc2cc(Cl)ccc12

InChI Key InChIKey=WVNRZDBXKCFYIM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324740   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324740(1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- ben...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent