BDBM324746 1'-({5-Chloro-1-[2- (cyclopropylsulfonyl)ethyl]-1H- benzimidazol-2- yl}methyl)spiro[cyclopropane-1,3'- pyrrolo[2,3-c]pyridin]-2'(1'H)-one::US10189838, Example 36-2

SMILES Clc1ccc2n(CCS(=O)(=O)C3CC3)c(CN3C(=O)C4(CC4)c4ccncc34)nc2c1

InChI Key InChIKey=ZFCXAGRCONBPGB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324746   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324746(1'-({5-Chloro-1-[2- (cyclopropylsulfonyl)ethyl]-1H...)
Affinity DataEC50:  8nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent