BDBM326983 1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benzyl}-2- methylpyrrolidine::US11957671, Compound 77::US9662339, 77

SMILES CC1CCCN1Cc1ccc(cc1)[C@H]1COc2ccccc2O1

InChI Key InChIKey=XNGYOAFTBGGDSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326983   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM326983(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM326983(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent