BDBM327133 4-[(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3-yl]benzyl}piperidin-4- yl)methyl]benzoic acid::US11957671, Compound 234::US9662339, 234

SMILES OC(=O)c1ccc(CC2CCN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)CC2)cc1

InChI Key InChIKey=DSGMDOGUYORMQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327133   

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM327133(4-[(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]p...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM327133(4-[(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]p...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent