BDBM327164 US9662339, 247::[(1alpha,5alpha,6alpha)-3-[(S)-4-(2,3-dihydro- [1,4]dioxino[2,3-b]pyridin-3-yl)- benzyl]-3-aza- bicyclo[3.1.0]hexane]-6- carboxylic acid ((S)-2-hydroxy- propyl)-amide

SMILES C[C@H](O)CNC(=O)[C@@H]1[C@H]2CN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)C[C@@H]12

InChI Key InChIKey=NMGMYBVVXDVBGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327164   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327164([(1alpha,5alpha,6alpha)-3-[(S)-4-(2,3-dihydro- [1...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent