BDBM327199 US9662339, 282::{1-[(S)-4-(2,3-dihydro- [1,4]dioxino-[2,3-b]pyridin-3-yl)- benzyl]-spiro-[3H-indole-3,4'- piperidine]-1(2H)-urea

SMILES NC(=O)N1CC2(CCN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)CC2)c2ccccc12

InChI Key InChIKey=BAINQKFXKYEGKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327199   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327199({1-[(S)-4-(2,3-dihydro- [1,4]dioxino-[2,3-b]pyrid...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent