BDBM327839 US9663476, Compound 48::[(R)-2-methyl-4-[(R)-(3′-methyl-biphenyl-4-yl)-phenyl-methyl]-piperazin-1-yl]-acetic acid

SMILES CCc1c(N2CCN(C(=O)CNC(=O)c3cccc(O)c3F)CC2)c(=O)n2nc(N3CCOCC3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1F

InChI Key InChIKey=UJFSHJIHSJJHAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327839   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Danatlas Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 327839BDBM327839(US20260015358, Example 252)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details US Patent