BDBM327856 5-chloro-N-[2- (hydroxymethyl)-3-[1- methyl-5-[[5- (morpholine-4- carbonyl)pyridin-2- yl]amino]-6- oxopyridin-3- yl]phenyl]-1,3- dihydroisoindole-2- carboxamide::US9663494, Compound 4

SMILES Cn1cc(cc(Nc2ccc(cn2)C(=O)N2CCOCC2)c1=O)-c1cccc(NC(=O)N2Cc3ccc(Cl)cc3C2)c1CO

InChI Key InChIKey=WXEUUUOQUSWAOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327856   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327856(5-chloro-N-[2- (hydroxymethyl)-3-[1- methyl-5-[[5-...)
Affinity DataIC50: 31.9nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent