BDBM327963 US10377742, Compound 100::US9663496, Compound 100::cis-1-(4-cyanobenzyl)-3- fluoropiperidin-4-yl)-5- (4-(4- fluorobenzyl)piperazine- 1-carbonyl)picolinamide

SMILES F[C@H]1CN(Cc2ccc(cc2)C#N)CC[C@H]1NC(=O)c1ccc(cn1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key InChIKey=GGMOGBNZFSCMDK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327963   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327963(US9663496, Compound 100 | cis-1-(4-cyanobenzyl)-3-...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327963(US9663496, Compound 100 | cis-1-(4-cyanobenzyl)-3-...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent