BDBM328051 (4-(4- fluorobenzyl)piperazin- 1-yl)(6-(4-(4- methoxybenzoyl) piperidin-1-yl)pyridin-3- yl)methanone::US10377742, Compound 189::US9663496, Compound 189

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cn1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key InChIKey=CHWFYLUDMGYJQK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328051   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328051(US9663496, Compound 189 | (4-(4- fluorobenzyl)pipe...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328051(US9663496, Compound 189 | (4-(4- fluorobenzyl)pipe...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent