BDBM328343 6-(4-(2,4- difluorobenzoyl) piperidine-1-carbonyl)- N-(6-(4- (dimethylcarbamoyl) phenoxy)pyridin-3- yl)nicotinamide::US10377742, Compound 481::US9663496, Compound 481

SMILES CN(C)C(=O)c1ccc(Oc2ccc(NC(=O)c3ccc(nc3)C(=O)N3CCC(CC3)C(=O)c3ccc(F)cc3F)cn2)cc1

InChI Key InChIKey=CSMZDTSEHGVTML-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328343   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328343(US9663496, Compound 481 | 6-(4-(2,4- difluorobenzo...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328343(US9663496, Compound 481 | 6-(4-(2,4- difluorobenzo...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent