BDBM328346 6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N-(1-(4-methoxybenzyl) piperidin-4-yl)-N- methylnicotinamide::US10377742, Compound 484::US9663496, Compound 484

SMILES COc1ccc(CN2CCC(CC2)N(C)C(=O)c2ccc(nc2)C(=O)N2CCC(CC2)C(=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=HHOJNLQASSTSAG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328346   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328346(US9663496, Compound 484 | 6-(4-(4-methoxybenzoyl) ...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328346(US9663496, Compound 484 | 6-(4-(4-methoxybenzoyl) ...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent