BDBM328350 N-(6-(4- acetylphenoxy)pyridin- 3-yl)-6-(4-(4- (dimethylcarbamoyl) phenoxy)piperidine-1- carbonyl)nicotinamide::US10377742, Compound 488::US9663496, Compound 488

SMILES CN(C)C(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)Nc2ccc(Oc3ccc(cc3)C(C)=O)nc2)cc1

InChI Key InChIKey=IDAXHXKLJMZMTG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328350   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328350(US9663496, Compound 488 | N-(6-(4- acetylphenoxy)p...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328350(US9663496, Compound 488 | N-(6-(4- acetylphenoxy)p...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent