BDBM328358 N-(6-(4- fluorophenoxy)pyridin- 3-yl)-6-(4-(4- (pentafluorosulfanyl) phenoxy)piperidine-1- carbonyl)nicotinamide::US10377742, Compound 496::US9663496, Compound 496

SMILES Fc1ccc(Oc2ccc(NC(=O)c3ccc(nc3)C(=O)N3CCC(CC3)Oc3ccc(cc3)S(F)(F)(F)(F)F)cn2)cc1

InChI Key InChIKey=BPLWMEIZMICBAU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328358   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328358(US9663496, Compound 496 | N-(6-(4- fluorophenoxy)p...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328358(US9663496, Compound 496 | N-(6-(4- fluorophenoxy)p...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent