BDBM328742 1,1,1-trifluoro-2-methylpropan- 2-yl ((S)-2-(((1R,2S)-2- cyanocyclopropane- carboxamido)methyl)-4-((4- fluorophenyl)sulfonyl)-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34AU
SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CNC(=O)[C@@H]3C[C@@H]3C#N)CN(c2c1)S(=O)(=O)c1ccc(F)cc1)C(F)(F)F
InChI Key InChIKey=MLHOZCZKFZNJFS-DKSSEZFCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328742
Affinity DataIC50: 3.94nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair