BDBM328794 1,1,1-trifluoro-2-methylpropan- 2-yl ((S)-4-((3- (difluoromethoxy)-1-ethyl-1H- pyrazol-4-yl)sulfonyl)-2- (((1S,2S)-2- fluorocyclopropane- carboxamido)methyl)-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34CV
SMILES CCn1cc(c(OC(F)F)n1)S(=O)(=O)N1C[C@H](CNC(=O)[C@@H]2C[C@@H]2F)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12
InChI Key InChIKey=RQKYEPSQYOWTPZ-ZNMIVQPWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328794
Affinity DataIC50: 4.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair