BDBM328876 (S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((3-chloro- 4-fluorophenyl)sulfonyl)-2-((N- methylmethylsulfonamido) methyl)-3,4-dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 41A

SMILES CN(C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(Cl)c1)S(C)(=O)=O

InChI Key InChIKey=OZCNDYRJZTYFBD-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328876   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328876((S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((3-ch...)
Affinity DataIC50:  4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent