BDBM329165 4-(5-chloro-6-(2,4,5- trichlorophenoxy)-3-pyridinyl)- 2-fluoro-5-methyl-N- (methylsulfonyl)benzamide::4-(5-chloro-6-(2,4,5-trichlorophenoxy)-3-pyridinyl)-2-fluoro-5-methyl-N-(methylsulfonyl)benzamide::US9663508, Example 667::US9663508, Example 668

SMILES Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(Oc2cc(Cl)c(Cl)cc2Cl)c(Cl)c1

InChI Key InChIKey=DDFXGXCKPYWBGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 329165   

LigandPNGBDBM329165(US9663508, Example 667 | US9663508, Example 668 | ...)
Affinity DataIC50: 50.5nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandPNGBDBM329165(US9663508, Example 667 | US9663508, Example 668 | ...)
Affinity DataIC50: 97nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandPNGBDBM329165(US9663508, Example 667 | US9663508, Example 668 | ...)
Affinity DataIC50: 7.45E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandPNGBDBM329165(US9663508, Example 667 | US9663508, Example 668 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent