BDBM329281 (S)-4-(2-fluoro-4-methoxyphenyl)-7-[1-(2-methylpyrimidin-5-yl)propan-2(R or S)-yl]quinoline-2-carboxamide::US9663506, Example 8-11

SMILES COC(=O)c1cc(-c2ccc(OC)cc2F)c2ccc(cc2n1)[C@@H](C)Cc1cnc(C)nc1

InChI Key InChIKey=KNOJZZCRWJYAID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329281   

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329281((S)-4-(2-fluoro-4-methoxyphenyl)-7-[1-(2-methylpyr...)
Affinity DataIC50: 6nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent